Scientists Are Developing ‘Injectable Bandage’ That Can Heal The Internal Injuries.

Scientists Are Developing ‘Injectable Bandage’ That Can Heal The Internal Injuries.

A team of the scientists, including one of Indian-origin, have developed an ‘injectable bandage’ that is a therapeutic gel which can heal potentially fatal internal injuries.

A penetrating injury from the shrapnel is a severe obstacle of overcoming the battlefield wounds that ultimately lead to death.

Given the high mortality rates due to a haemorrhaging, there is an unmet need to quickly self-administer materials that to prevent fatality due to an excessive blood loss.

With a gelling agent commonly using in preparing pastries, researchers from the Texas A&M University in the US have successfully fabricated an injectable bandage to stop bleeding and promote the wound healing.

The Researchers used the kappa-carrageenan and nano silicate to form injectable hydrogels to promoting hemostasis the process to stop bleeding and facilitating wound healing that is a controlled release of the therapeutics.

“Injectable hydrogels are promising the materials for achieving hemostasis in case of internal injuries and bleeding, as these biomaterials can introducing into a wound site using minimally invasive approaches.

Scientists Are Developing ‘Injectable Bandage’ That Can Heal The Internal Injuries.

“An ideal injectable bandage should solidify after injection in the wound area and promote a natural clotting cascade. Also, the injectable bandage should initiate the wound healing response after achieving the hemostasis,” says Gaharwar.

The study, publishing in the journal Acta Biomaterialia, uses a conventional thickening agent which is known as kappa-carrageenan, obtaining from seaweed, to design injectable hydrogels.

Hydrogels are a 3D water-swollen polymer network, similar to the Jell-O, simulating the structure of the human tissues.

When kappa-carrageenan is mixing up with clay-based nanoparticles, injectable gelatine is obtaining. The charged characteristics of clay-based nanoparticles are providing a hemostatic ability to the hydrogels.

Specifically, plasma protein and platelets from blood adsorbing in the gel surface to trigger blood clotting cascading.

We found that these injectable bandages can show a prolonging release of the therapeutics that can use to heal the wound,” says Giriraj Lokhande, a graduate student in Gaharwar’s lab.

“The negative surface charge of nanoparticles is enabled electrostatic interactions with the therapeutics thus resulting in the slow release of therapeutics,” says Lokhande.

So, these are the points to describing on the Scientists are developing ‘injectable bandage’ that can heal the internal injuries.

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